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制药工程系

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刘涛

职务/职称 无/讲师

学历/学位 研究生/博士

电子邮箱 liutao@aku.edu.cn

出生年月 1992-02

研究方向 有机合成方法学

毕业学校 陕西科技大学

研究工作简介:

(1)杂环、小分子化合物的构建及药物中间体的合成;

(2)不对称金属催化。

代表性成果:

2023

(1)Liu T.,Yao T L.,*Guo R H., Qin X Y. Palladium-catalyzed cascade cyclization/ intramolecular redox-relay Heck arylation of alkenols: access to tetrahydro-β-carbolines from 2-(hydroxyalkenynyl)sulfonanilides,Org. Chem. Front., 2023, 10: 3504.

(2) Yao T L.,*Zhu R.,Liu T.Synthesis of 3-aminoindenes andcis-1-aminoindanes by Zn(OTf)2-catalyzed cyclization ofo-alkynylbenzaldehydes with tertiary alkyl primary amines,Chem. Commun., 2023,59, 14325.

2022

(1) Yao T L.,*Zhao S J.,#Liu T.,#Wu Y T., Ma Y H., Li T., Qin X Y. Transition -metal-free approaches to 2,3-diarylated indenones from 2-alkynylbenzaldehydes and phenols with tunable selectivity,Chem. Commun., 2022,58, 4592.

2021

(1)Liu T., Yao T L.,*Zhang F., Ju Y., Tan J J. Cleavage and reassembly of the C=O bond of 2-alkynylbenzaldehydes: A metal-free access to inden-1-ones,J. Org. Chem., 2021, 86:9455.

(2) Yao T L.,*Hui J Z.,Liu T., Li T. Palladium-catalyzed three-component carbocarbonation of arynes: expeditious synthesis ofo-alkylated arylacrylates and stilbenes,J. Org. Chem., 2021, 86: 5477.

2020

(1) Guo Z.,1Liu T.,1Liang X j., Wu Y T., Yao T L.*Cs2CO3catalyzed intramolecular aminocarbonylation of alkynes: synthesis of 3-amino-1H-inden-1-ones fromN-tert-butyl-2-(1-alkynyl)benzaldimines,Adv. Synth. & Catal., 2020, 362: 1053.

2017

(2) Yao T L.,*Liu T., Zhang C H. Palladium-catalyzed domino Heck/intermolecular cross-coupling: efficient synthesis of 4-alkylated isoquinoline derivatives,Chem. Commun., 2017, 53: 2386.

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